A C14-polyacetylenic glucoside with an α-pyrone moiety and four C10-polyacetylenic glucosides from Mediasia macrophylla

Polyacetylenic glucosides (1-5) were isolated from the MeOH extract of Mediasia macrophylla. Their structures were established by spectroscopic analyses. Compounds 2-4 were the first examples of C10-polyacetylenic glucosides found in the family Umbelliferae, while compound 1 was a unique polyacetylenic glucoside possessing an α-pyrone moiety.