Cytotoxic sesquiterpenoids from Winteraceae of Caledonian rainforest

One secobutanolide, 2 butanolides and 6 drimane sesquiterpenoids, along with 6 known drimanes were isolated from Zygogynum spp. (Winteraceae). Their structures were elucidated through analysis of spectroscopic data. Compounds with a dialdehyde function exhibited significant inhibitory activities in the in vitro cytotoxic assays against KB, HL60 and HCT116 cancer cell lines.