Steroidal saponins from the stem of Yucca elephantipes

Ten steroidal saponins with cis-fused A/B ring, including a smilagenin glycoside, elephanoside A (4), and the five furostanol bisdesmosides, elephanosides B-F (6-10), were isolated from the stems of Yucca elephantipes Regel. (Agavaceae). Of these, two known smilagenin glycosides, Ys-II (1) and Ys-IV (2), showed moderate antifungal activity against Candida albicans and Cryptococcus neoformans.