Cytotoxic triterpenoid saponins from the fruits of Aesculus pavia L.

The isolation and structure elucidation of 13 triterpenoid saponins, named aesculiosides IIe-IIk and IIIa-IIIf from the fruits of Aesculus pavia L. are reported. Some saponins from this plant showed cytotoxic activity against 59 cell lines from nine different human cancers.