Bioactive constituents from roots of Bursera tonkinensis

Bioassay directed-fractionation led to the isolation of 12 compounds, including the lignan (A), the phenylpropane derivative (B), and the neolignan (C) from the roots of Bursera tonkinensis Guillaum (Burseraceae). The structures were determined by spectroscopic methods. Of these only 4′-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines.