4-Benzyl-3-phenyl-5H-furan-2-one, a vasodilator isolated from Malbranchea filamentosa IFM 41300

Screening of Malbranchea filamentosa IFM 41300 for bioactive compounds led to the discovery of the furanone derivative (1) as a vasodilator and the isolation of erythroglaucin (2). The structure of 1 was established on the basis of spectroscopic and chemical investigations.