کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5176438 | 1502443 | 2015 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Geranylated tetraoxygenated xanthones from the pericarp of Garcinia pedunculata Geranylated tetraoxygenated xanthones from the pericarp of Garcinia pedunculata](/preview/png/5176438.png)
- Isolation of natural products from the pericarp of Garcinia pedunculata.
- Structure elucidation of thirteen compounds.
- Characterisation of three new geranylated tetraoxygenated xanthones, pedunxanthones D-F.
- Evaluation of cytotoxicity against HeLa and NCI-H460 cells of the isolated compounds using an SRB assay.
Three new xanthones, pedunxanthones D-F (1-3), along with ten known compounds, were isolated from a chloroform extract of the pericarp of Garcinia pedunculata. Their structures were determined using spectroscopic techniques. Cytotoxicity against HeLa and NCI-H460 cells of the isolated compounds using an SRB assay was evaluated with pedunxanthone D (1) as the most active compound (IC50 24.9 ± 0.4 and 26.1 ± 1.5 μg/ml, respectively).
Journal: Phytochemistry Letters - Volume 13, September 2015, Pages 119-122