Glutathione S-transferase inhibitory, free radical scavenging, and anti-leishmanial activities of chemical constituents of Artocarpus nobilis and Matricaria chamomilla

Phytochemical studies on Artocarpus nobilis and Matricaria chamomilla resulted in the isolation of compounds 1-16. Compound (10) was found to be new. All of the isolates exhibited different levels of glutathione S-transferase (GST), free radical scavenging and anti-leishmanial activities. Compounds 5-9 were found to exhibit potent GST inhibition activity than ethacrynic acid, a standard GST inhibitor.