Guttiferones Q-S, cytotoxic polyisoprenylated benzophenones from the pericarp of Garcinia cochinchinensis

► Chemical constituents of the pericarp of Garcinia cochinchinensis. ► Isolation and structure elucidation of nine compounds. ► Three new polyisoprenylated benzophenones, guttiferones Q-S, and six known compounds. ► Cytotoxicity towards three human cancer cell lines, MCF-7, Hela, and NCI-H460. ► Guttiferone Q showing potent activity (IC50 2.74-4.04 μg/ml).