Saponins and alkaloids from Abuta grandifolia

► Isolation and structural elucidation of five new saponins from Abuta grandifolia. ► This is the first report of the isolation of saponins in genus Abuta. ► Only the third report on saponins in Menispermaceae. ► Isoimerubrine, pareirubrines A and B, and stepharine described in A. grandifolia.