Novel cassane diterpenes from the seeds of Caesalpinia minax

Three new cassane diterpenes, sucutiniranes G (1), H (2) and I (3) were isolated from the seeds of Caesalpinia minax Hance. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, CD, 1D and 2D NMR). All compounds were evaluated for cytotoxic activities against MCF-7 and HepG-2 human cancer cell lines.

Highlights► Three novel cassane-type diterpenes were isolated from the seeds of Caesalpinia minax Hance. ► The absolute configuration of the new compounds has been determined. ► The new compounds were evaluated for cytotoxic activities against MCF-7 and HepG-2 human cancer cell lines.