کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5210802 | 1382917 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation of chitosan-g-polylactide graft copolymers via self-catalysis of phthaloylchitosan and their complexation with DNA
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The graft copolymer of chitosan-g-polylactide (CS-g-PLA) was synthesized successfully through ring-opening polymerization of lactide onto phthaloyl-protected chitosan by a self-catalysis strategy. After graft copolymerization, the phthaloyl groups were deprotected to regenerate free amino groups in the CS-g-PLA. FT-IR and NMR were used to characterize the graft copolymers both before and after the deprotection. We observed that degradation of the grafted PLA chains occurred in the alkaline deprotection process, and this process was optimized. Moreover, the CS-g-PLA containing the amino-polysaccharide backbone was formed into a polyelectrolyte complex with DNA. The resultant CS-g-PLA/DNA complexes were determined to be about 60Â nm, with a positive charge above an N/P of 4/1.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reactive and Functional Polymers - Volume 70, Issue 5, May 2010, Pages 301-305
Journal: Reactive and Functional Polymers - Volume 70, Issue 5, May 2010, Pages 301-305
نویسندگان
Li Liu, Aibin Shi, Shengrong Guo, Yue'e Fang, Song Chen, Jin Li,