کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5212352 | 1383113 | 2017 | 7 صفحه PDF | دانلود رایگان |
Seven new alkaloids belonging to three typical classes, isolated from an ethanolic extract of Pandanus amaryllifolius, were applied to establish the models in structural elucidation. The first type [pandanusines A and B (1 and 2)] was applied to alkaloids with a diazaspirocyclic ring system. The absolute stereochemistry of aminal carbon is determined by analysis of J-based configuration analysis and circular dichroism spectroscopy, which has never been revealed before. The second type [pandalizines C-E (3-5)], the stereochemistry of unusual indolizinone with chiral hydroxyl substitutions were determined by circular dichroism spectroscopy and vibrational circular dichroism experiments. The last type [norpandamarilactonines C and D (6 and 7)], a comparing model in determination of diastereomers of pyrrolidinyl α,β-unsaturated γ-lactone alkaloids was established. Our study provides solutions for a challenging subject in stereochemistry determination for three different types of Pandanus alkaloids.
Seven new alkaloids, pandanusines A and B (1 and 2), pandalizines C-E (3-5), and norpandamarilactonines C and D (6 and 7) were isolated from Pandanus amaryllifolius. The stereochemistry determination for three different types of Pandanus alkaloids was established.62
Journal: Tetrahedron - Volume 73, Issue 25, 22 June 2017, Pages 3423-3429