کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5215504 | 1383233 | 2015 | 5 صفحه PDF | دانلود رایگان |
Electrochemical oxidation of catechols in the presence of 4-mercapto-benzoic acid as nucleophile have been studied in aqueous acetate buffer solution using cyclic voltammetry and control potential coulometry. The cyclic voltammetric results showed that an electro oxidative/Michael type sequential reaction occurs between the 4-mercaptide anion and electrochemically generated o-bezoquinones leading to the corresponding products 4a-4b.The mechanism electrochemical reaction is proved as an EC pathway using controlled-potential coulometry. The antimicrobial activity of these newly synthesized compounds were screened against Gram-positive and Gram-negative bacteria namely, Bacillus subtilis, Staphylococcus aureus, Escherichia coli. These newly syntheses compounds showed good antimicrobial activity.
Journal: Tetrahedron - Volume 71, Issue 11, 18 March 2015, Pages 1674-1678