کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5217140 | 1383286 | 2014 | 7 صفحه PDF | دانلود رایگان |
Caffeine (1,3,7-trimethylxanthine) is a chemical substance associated with everyday human life. In order to recognize caffeine in water, six water-soluble acyclic phane compounds composed of three aromatic rings were examined as artificial receptors. 1H NMR titration experiments revealed that 6,6â²-[1,3-phenylenebis(carbonylimino)]bis-1,3-naphthalenedisulfonate had the highest binding ability for caffeine, with a binding constant (Kb) of 127±5 Mâ1 at 300 K. While this phane compound also formed a complex with theophylline (1,3-dimethylxanthine) at around half the value of the binding constant for caffeine (Kb=64±4 Mâ1), it showed weak or little complexation for adenosine, guanosine, inosine, and their 5â²-phosphates (sodium salts of adenylic acid, guanylic acid, and inosinic acid).
Journal: Tetrahedron - Volume 70, Issue 4, 28 January 2014, Pages 845-851