کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5218836 1383339 2012 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stereospecific novel glycosylation of hydroxy β-lactams via iodine-catalyzed reaction: a new method for optical resolution
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Stereospecific novel glycosylation of hydroxy β-lactams via iodine-catalyzed reaction: a new method for optical resolution
چکیده انگلیسی

Glycosylation of racemic and optically active α-hydroxy β-lactams by reaction with a few glycal derivatives in the presence of catalytic amounts of iodine has provided stereospecific formation of α-glycosides. This method has been extended for the preparation of optically active hydroxy β-lactams in excellent yields. The stereochemistry and nature of the glycals as well as the stereochemistry of the β-lactam ring has a profound influence for effective glycosylation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 68, Issue 52, 30 December 2012, Pages 10769-10779
نویسندگان
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