Laccase-catalyzed reaction of 3-tert-butyl-1H-pyrazol-5(4H)-one with substituted catechols using air as an oxidant

The laccase-catalyzed reaction of 3-tert-butyl-1H-pyrazol-5(4H)-one with a number of catechols and aerial oxygen as an oxidant selectively affords 4-substituted 3-tert-butyl-1H-pyrazol-5-ol derivatives with yields ranging from 77 to 99%.