کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5219076 | 1383346 | 2012 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
One-pot formation of aza-enolates from secondary amines and condensation to esters and alkyl bromides
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: One-pot formation of aza-enolates from secondary amines and condensation to esters and alkyl bromides One-pot formation of aza-enolates from secondary amines and condensation to esters and alkyl bromides](/preview/png/5219076.png)
چکیده انگلیسی
Starting from commercial secondary amines, a one-pot procedure allows a direct access to enaminones through a one-pot deprotonation/oxidation/in situ re-deprotonation/acylation sequence without intermediate isolation of the intermediate Schiff base or its corresponding enamine tautomer. An alternative one-pot sequence involving a similar oxidation step followed by one or two alkylation steps yields, after acidic work-up, functionalized ketones directly from the parent amine. This process has been applied to an expeditious synthesis of the male aggregation pheromone of the cereal leaf beetle Oulema melanopus.
Graphical Abstract
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 68, Issue 29, 22 July 2012, Pages 5882-5889
Journal: Tetrahedron - Volume 68, Issue 29, 22 July 2012, Pages 5882-5889
نویسندگان
Alice Chevalley, Jean-Pierre Férézou,