کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5220377 1383386 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development of convergent synthetic method for saccharide-linked ethynylpyridine foldamers by Huisgen reaction
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Development of convergent synthetic method for saccharide-linked ethynylpyridine foldamers by Huisgen reaction
چکیده انگلیسی

Based on 'click chemistry', the new convergent synthesis to a variety of saccharide-linked 2,6-pyridylene ethynylene 'ethynylpyridine' foldamers was developed. Ethynylpyridine 6-, 9-, and 12-meric blocks were linked with 1,7-octadiyne linker block by Sonogashira reaction, and joined with azido group-introduced glucoside, galactoside, and mannoside templates by Huisgen reaction. The resulting saccharide-linked ethynylpyridine foldamers exhibited typical circular dichroism to indicate the formation of a helical structure by intramolecular hydrogen bonds.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 68, Issue 23, 10 June 2012, Pages 4353-4361
نویسندگان
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