کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5220740 | 1383398 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Asymmetric epoxidation of (Z)-enol esters catalyzed by titanium(salalen) complex with aqueous hydrogen peroxide
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Titanium(salalen) complex 1 was an effective catalyst for asymmetric epoxidation of enol esters. Although (E)-enol esters were reluctant to proceed, (Z)-enol esters underwent asymmetric epoxidation to give the epoxides in high yields with high enantioselectivity ranging from 86 to >99% ee in the presence of aqueous hydrogen peroxide as the stoichiometric oxidant. Complete enantioselectivity was observed in the reaction of (Z)-3,3-dimethylbut-1-en-1-yl 4-methoxybenzoate. The obtained epoxide was readily transformed into the corresponding 1,2-diol by reduction with lithium borohydride without erosion of the high enantiomeric excess.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 67, Issue 35, 2 September 2011, Pages 6474-6478
Journal: Tetrahedron - Volume 67, Issue 35, 2 September 2011, Pages 6474-6478
نویسندگان
Kazuhiro Matsumoto, Chao Feng, Satoshi Handa, Takuya Oguma, Tsutomu Katsuki,