کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5222664 1383461 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Visualization and quantification of anisotropic effects on the 1H NMR spectra of 1,3-oxazino[4,3-a]isoquinolines-indirect estimates of steric compression
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Visualization and quantification of anisotropic effects on the 1H NMR spectra of 1,3-oxazino[4,3-a]isoquinolines-indirect estimates of steric compression
چکیده انگلیسی

The anisotropic effects of the phenyl, α- and β-naphthyl moieties in four series of 1,3-oxazino[4,3-a]isoquinolines on the 1H chemical shifts of the isoquinoline protons were calculated by employing the Nucleus Independent Chemical Shift (NICS) concept and visualized as anisotropic cones by a through-space NMR shielding grid. The signs and extents of these spatial effects on the 1H chemical shifts of the isoquinoline protons were compared with the experimental 1H NMR spectra. The differences between the experimental δ (1H)/ppm values and the calculated anisotropic effects of the aromatic moieties are discussed in terms of the steric compression that occurs in the compounds studied.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 65, Issue 38, 19 September 2009, Pages 8021-8027
نویسندگان
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