کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5223665 | 1383494 | 2010 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A two-step mimic for direct, asymmetric bromonium- and chloronium-induced polyene cyclizations
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A two-step mimic for direct, asymmetric bromonium- and chloronium-induced polyene cyclizations A two-step mimic for direct, asymmetric bromonium- and chloronium-induced polyene cyclizations](/preview/png/5223665.png)
چکیده انگلیسی
Although direct, asymmetric, halonium-induced cyclizations have proven difficult to achieve in the absence of enzymes, this report provides a two-step alternative based on reacting polyenes with chiral mercury(II) complexes to afford a number of polycyclic organomercurials that can be subsequently converted, with retention, into their corresponding chlorine, bromine, and iodine derivatives in good yield and enantioselectivity. A five-step asymmetric total synthesis of the natural product 4-isocymobarbatol is also described.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 66, Issue 26, 26 June 2010, Pages 4796-4804
Journal: Tetrahedron - Volume 66, Issue 26, 26 June 2010, Pages 4796-4804
نویسندگان
Scott A. Snyder, Daniel S. Treitler, Andreas Schall,