کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5226709 1383583 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New convenient synthesis of 2,3-diaminothieno[2,3-d]pyrimidin-4(3H)-one derivates from substituted alkyl 2-(1H-tetrazol-1-yl)thiophene-3-carboxylates
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
New convenient synthesis of 2,3-diaminothieno[2,3-d]pyrimidin-4(3H)-one derivates from substituted alkyl 2-(1H-tetrazol-1-yl)thiophene-3-carboxylates
چکیده انگلیسی

4,5-Disubstituted and 4-substituted alkyl 2-amino-thiophene-3-carboxylates react with triethyl orthoformate and sodium azide in acetic acid to yield new 2-(1H-tetrazol-1-yl)-4-R1-5-R2-thiophene derivates. It was established that the reaction of these tetrazoles with hydrazine generates the insufficiently studied 2,3-diaminothieno[2,3-d]pyrimidin-4(3H)-one system. It is significant that the reaction mentioned above is the unique tetrazole ring cleavage under the action of hydrazine.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 64, Issue 7, 11 February 2008, Pages 1430-1434
نویسندگان
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