کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5229620 1383667 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reaction of α-halo ketone with 2-aminothiol: a new synthesis of thiazolidines with the oxo group migrated to the original position occupied by halogen atom
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Reaction of α-halo ketone with 2-aminothiol: a new synthesis of thiazolidines with the oxo group migrated to the original position occupied by halogen atom
چکیده انگلیسی

The reaction of 2-bromo-3-oxo steroids with 2-aminoethanethiol led to the stereoselective formation of spiro[steroid-3,2′-thiazolidin]-2-ones as the major product. With both cyclic and acyclic α-halo alkanones, the reaction gave the thiazolidines with the oxo group migrated to the original position occupied by the halogen atom. In addition, it was found that the use of microwaves affords improvement of yields and shortening the reaction time in comparison with usual conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 63, Issue 36, 3 September 2007, Pages 8932-8938
نویسندگان
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