کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5230545 1383698 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
P-alkene bidentate ligands: an unusual ligand effect in Pd-catalysed Suzuki reactions
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
P-alkene bidentate ligands: an unusual ligand effect in Pd-catalysed Suzuki reactions
چکیده انگلیسی

The versatile reagent bis(diphenylphosphino)benzaldehyde was used to prepare a variety of electronically and sterically varied ligands using Wittig or aldol methodology in high yields. Pd-catalysed Suzuki reactions were evaluated using these ligands. The influence of the functional group on the alkene, which is in direct conjugation with the phosphorus centre of the ligand, was visible in the activity profiles of the reactions. In general, the activity and stability of the Pd-ligand system increased as electron deficiency and steric bulk increased at the alkene. Furthermore, the ligands could be used at decreased catalyst loadings with improved yields and did not themselves participate in the reactions as substrates.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 63, Issue 7, 12 February 2007, Pages 1624-1629
نویسندگان
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