Palladium-catalyzed one-pot Suzuki-Miyaura cross coupling followed by oxidative lactonization: a novel and efficient route for the one-pot synthesis of benzo[c]chromene-6-ones

sA number of 6H-benzo[c]chromene-6-ones, 5H-naphtho[1,2-c]chrome-5-ones, and 6H-naphtho[2,1-c]chromene-6-one have been synthesized starting with 2-hydroxyphenylboronic acid and o-bromobenzaldehyde or o-bromonaphthalene carboxaldehyde derivatives via a one-pot Suzuki-Miyaura cross coupling followed by oxidative lactonization reactions. The overall transformation consists of three reactions: Suzuki-Miyaura cross coupling, hemi-acetal formation, and oxidation.