کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5265429 | 1385284 | 2013 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A cross-linked polystyrene supported hindered lithium amide as a deprotonation reagent for α-methylation of lactic acid
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A cross-linked polystyrene supported hindered lithium amide as a deprotonation reagent for α-methylation of lactic acid A cross-linked polystyrene supported hindered lithium amide as a deprotonation reagent for α-methylation of lactic acid](/preview/png/5265429.png)
چکیده انگلیسی
The poly(tetramethylglycolide) [PTMG] is currently attracting a lot of interest as an upgraded feedstock recyclable material derived from poly(l-lactic acid). To achieve more efficient process of PTMG production from lactic acid, hindered lithium amide supported by cross-linked polystyrene as a deprotonation reagent was prepared from commercially available Merrifield resin, 2,2,6,6-tetramethyl-4-pipedinol, and n-butyllithium. A polymer-supported lithium 2,2,6,6-tetramethylpiperidide/methyl iodide system was found to be an efficient condition for the α-methylation reaction of lactic acid derivatives, giving excellent yields of α-methylated products (98%) under room temperature for a very short reaction time.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 54, Issue 32, 7 August 2013, Pages 4320-4323
Journal: Tetrahedron Letters - Volume 54, Issue 32, 7 August 2013, Pages 4320-4323
نویسندگان
Kohtaro Watanabe, Yoshito Andou, Yoshihito Shirai, Haruo Nishida,