کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5266871 1385322 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Enantioselective organocatalytic Michael addition of 2-arylacetates and 2-arylacetonitriles having an electron-withdrawing group to α,β-unsaturated aldehydes
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Enantioselective organocatalytic Michael addition of 2-arylacetates and 2-arylacetonitriles having an electron-withdrawing group to α,β-unsaturated aldehydes
چکیده انگلیسی
The asymmetric organocatalytic Michael addition reaction of 2-arylacetates and 2-arylacetonitriles having an electron-withdrawing group to α,β-unsaturated aldehydes has been established using diphenylprolinol trimethylsilyl (TMS) ether as organocatalyst. The 2-arylacetates and 2-arylacetonitriles having NO2-, CO2Me-, and CN-functional groups on the aromatic ring can be used in this reaction. The desired products were obtained with good to excellent yields and high enantioselectivities (up to 97% ee).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 53, Issue 23, 6 June 2012, Pages 2809-2812
نویسندگان
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