کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5269774 | 1385398 | 2014 | 9 صفحه PDF | دانلود رایگان |
The past decade has witnessed the significant advances of asymmetric organocatalytic fluorination, monofluoroalkylation, gem-difluoroalkylation, and trifluoromethylation. This digest summarizes the latest progress of these reactions. In the research area of asymmetric organocatalytic fluorination, a new catalysis concept, chiral anion phase-transfer catalysis strategy, has emerged and has proved to be highly efficient. Asymmetric organocatalytic monofluoroalkylation and gem-difluoroalkylation have been much less explored and the Lewis base/acid catalysis has been the most used strategy. Compared with electrophilic trifluoromethylation, nucleophilic trifluoromethylation has been intensively studied in the research field of asymmetric organocatalytic trifluoromethylation.
Journal: Tetrahedron Letters - Volume 55, Issue 45, 5 November 2014, Pages 6147-6155