Catalyst-free, ethylene glycol promoted one-pot three component synthesis of 3-amino alkylated indoles via Mannich-type reaction

- Catalyst free conditions for the synthesis of 3-amino alkylated indoles.
- This method is useful for large scale production of 3-amino alkylated indoles.
- Avoids the use of column chromatography for the purification of final products.
- Ethylene glycol is as a green promoted medium.