کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5270890 1385427 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Co2(CO)8 as a convenient in situ CO source for the direct synthesis of benzamides from aryl halides (Br/I) via aminocarbonylation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Co2(CO)8 as a convenient in situ CO source for the direct synthesis of benzamides from aryl halides (Br/I) via aminocarbonylation
چکیده انگلیسی


- Direct one pot synthesis of benzamides from wide variety of aryl halides.
- Cobalt carbonyl as an in situ CO source in microwave irradiation without CO gas.
- This is a functional group tolerant method.

A fast, mild, and functional group tolerant method for the direct synthesis of benzamides from aryl halides (Br, I) via aminocarbonylation, using solid Co2(CO)8 as a convenient CO source, has been demonstrated. The developed method is applicable to a wide variety of 1° and cyclic and acyclic 2° amines. Nitro substituted (o, m and p) aryl halides have easily been converted to the corresponding benzamides, without the reduction of the nitro group, in high yields using this in situ carbonylation methodology under microwave irradiation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 55, Issue 5, 29 January 2014, Pages 1006-1010
نویسندگان
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