Palladium(0) nanoparticle-catalyzed sp2 C-H activation: a convenient route to alkyl-aryl ketones by direct acylation of aryl bromides and iodides with aldehydes

Palladium(0) nanoparticles efficiently catalyze aliphatic aldehyde C-H functionalization by aryl halides to produce alkyl-aryl ketones in good yields. A wide range of substituted aryl and hetero-aryl bromides/iodides and open-chain aldehydes of varied chain length participated in this reaction.

Palladium(0) nanoparticles efficiently catalyze aldehyde C-H functionalization by aryl halides to produce alkyl-aryl ketones in good yields.