کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5272142 | 1385458 | 2013 | 5 صفحه PDF | دانلود رایگان |
An efficient one-pot protocol for the synthesis of (E)-nitroalkenes by reaction of aldehydes and nitroalkanes in the presence of polymer-bound triphenylphosphine, iodine and imidazole is described. Although the reaction works with similar efficiency with triphenylphosphine and its polymer-bound version, easy removal of the unwanted polymer-bound triphenylphosphine oxide and its recovery as triphenylphosphine provide the edge for practical application of the method.
An efficient protocol for the synthesis of (E)-nitroalkene by sequential one-pot reaction of aldehyde and nitroalkane in the presence of polymer-bound triphenylphosphine, iodine, and imidazole is described. One-step synthesis of nitroalkenes without using conventional dehydrating reagents, easy purification, and excellent yield of the products are some of the major advantages of the protocol.
Journal: Tetrahedron Letters - Volume 54, Issue 40, 2 October 2013, Pages 5500-5504