کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5272311 1385462 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Conoliferine and isoconoliferine, structurally novel alkaloid-lignan conjugates from Tabernaemontana corymbosa
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Conoliferine and isoconoliferine, structurally novel alkaloid-lignan conjugates from Tabernaemontana corymbosa
چکیده انگلیسی

Conoliferine and isoconoliferine were isolated from Tabernaemontana corymbosa as an unresolvable mixture of (1′S, 2′S)- and (1′R, 2′R)-diastereomers. These novel natural products are constituted from the union of an iboga alkaloid, ibogaine, and a lignan moiety, and represent the first instance of such an alkaloid-lignan conjugate. The structure was determined by spectroscopic methods, including the extensive use of NOE experiments for assignment of stereochemistry.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 50, Issue 27, 8 July 2009, Pages 3756-3759
نویسندگان
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