A facile access to substituted indoles utilizing palladium catalyzed annulation under microwave enhanced conditions

A facile access to differently substituted indoles using palladium catalyzed annulation reactions under microwave enhanced conditions has been achieved. A highly active and efficient catalytic system PdCl2/(A-taphos) for the synthesis of indole via palladium catalyzed ring annulation of ortho iodo anilines and aldehydes has been developed.

A highly active and efficient catalytic system PdCl2/A-taphos was employed for the synthesis of indoles via palladium catalyzed ring annulation of ortho iodo anilines and aldehydes.