کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5273488 1385491 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Are Cu(I)-mesoionic NHC carbenes associated with nitrogen additives the best Cu-carbene catalysts for the azide-alkyne click reaction in solution? A case study
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Are Cu(I)-mesoionic NHC carbenes associated with nitrogen additives the best Cu-carbene catalysts for the azide-alkyne click reaction in solution? A case study
چکیده انگلیسی
Copper(I)-catalyzed azide alkyne cycloaddition is now a widely used tool for the synthesis of elaborated compounds. Until now, few stable and efficient copper(I) catalysts are available despite the limitations inherent to approaches employing the in situ reduction of a CuII species to deliver the catalytic system. We report that the combination of a copper(I)-mesoionic N-heterocyclic carbene (MIC) with a phenanthroline derivative generates a highly active catalyst, functioning in aqueous alcoholic solvent, without the intervention of a reducing agent. This catalytic system surpasses related 'normal' N-heterocyclic carbene-based systems in their efficiency.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 54, Issue 14, 3 April 2013, Pages 1808-1812
نویسندگان
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