Regioselective synthesis of trifluoromethyl group substituted allylic amines via palladium-catalyzed allylic amination

The palladium-catalyzed regioselective allylic amination of α-trifluoromethylated allyl acetate occurred using Pd(OAc)2/DPPE and [Pd(π-allyl)(cod)]BF4/DPPF. The selective formation of the γ-product was attained by Pd(OAc)2/DPPE, while the α-product was obtained using [Pd(π-allyl)(cod)]BF4/DPPF.