کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5274191 1385505 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Macrocyclic 5-bromouracil derivatives: synthesis and transformation of a uracil ring
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Macrocyclic 5-bromouracil derivatives: synthesis and transformation of a uracil ring
چکیده انگلیسی

Cyclization of 1,3-bis(ω-bromoalkyl)-5-bromouracil with p-methoxybenzylamine or sodium sulfide led to a series of pyrimidinophanes containing heteroatoms in bridges. An unusual behaviour of the 5-bromouracil ring, namely its contraction into hydantoin units during the cyclization reactions with p-methoxybenzylamine was observed. Sodium sulfide does not affect the 5-bromouracil ring, and no transformation products were observed in the synthesis of pyrimidinophanes with sulfur bridges. A possible reaction mechanism is given.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 49, Issue 41, 6 October 2008, Pages 5994-5997
نویسندگان
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