Efficient ligand-free nickel-catalyzed C-S cross-coupling of thiols with aryl iodides

NiCl2·6H2O efficiently catalyzes the C-S bond formation by the cross-coupling of aryl iodides with thiols in tetrabutylammonium bromide (TBAB) in excellent yield. The reaction functions in air and the NiLn-TBAB can be recovered and recycled without the loss of activity.

NiCl2·6H2O has efficiently catalyzed the S-arylation of aromatic and benzyl thiols with aryl iodides in tetrabutylammonium bromide (TBAB) under air.