A new organocatalyst for 1,3-dipolar cycloadditions of nitrones to α,β-unsaturated aldehydes

The triflate salt resulting from the treatment of diphenyl-S-prolinol with trimethylsilyl triflate, catalyzes the addition of nitrones to α,β-unsaturated aldehydes to provide isoxazolidines in high yields and excellent diastereo- and enantioselectivities.