کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5276877 | 1385567 | 2007 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Efficient condensation of carboxylic acids with alcohols catalyzed by fluorous ammonium triflates Efficient condensation of carboxylic acids with alcohols catalyzed by fluorous ammonium triflates](/preview/png/5276877.png)
The use of fluorous ammonium salts as metal-free catalysts for the direct condensation of equimolar amounts of carboxylic acids and aliphatic alcohols has been investigated. Esterification reactions were thus conveniently carried out under mild fluorous biphasic conditions, in the presence of 1 mol % of fluorous ammonium triflate and without recourse to any additional water removal technique. Good to excellent ester yields were obtained in the case of primary and secondary aliphatic alcohols. The fluorous salt was easily recovered by simple phase separation and reused at least three times without considerable loss of activity.
Direct esterification of carboxylic acids with equimolar amounts of alcohols can be conveniently run under mild fluorous biphasic conditions in the presence of recoverable fluorous ammonium salts.
Journal: Tetrahedron Letters - Volume 48, Issue 17, 23 April 2007, Pages 3053-3056