A one-pot process for the enantioselective preparation of saturated secondary alcohols from propargyl ketones under hydrogen transfer conditions

Propargyl ketones can be directly transformed to enantio-enriched saturated secondary alcohols in a one-pot reaction using chiral RuCl[N-(tosyl)-1,2-diphenylethylenediamine)(p-cymene) and Pd/BaSO4 as catalysts, under transfer hydrogenation conditions.