Adenine-based receptor for dicarboxylic acids

The adenine-based fluorescent receptor 1 was designed and synthesized for the selective recognition of dicarboxylic acids in CH3CN. The recognition takes place through the Hoogsteen binding site of adenine with concomitant PET quenching of the anthracene moiety. The Hoogsteen cleft of the receptor is involved in carboxylic acid binding and is found to be selective for glutaric acid.