Rapid and efficient synthesis of 2-imidazolines and bis-imidazolines under ultrasonic irradiation

Rapid and efficient preparation of 2-imidazolines and bis-imidazolines by reaction of ethylenediamine with nitriles in the presence of catalytic amounts of sulfur under ultrasonic irradiation is reported. The advantages of this system are short reaction times, high yields and the ability to carry out large scale reactions.

Rapid and efficient preparation of 2-imidazolines and bis-imidazolines by nucleophilic addition of EDA to nitriles in the presence of catalytic amounts of sulfur under ultrasonic irradiation is reported.