کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5279856 1385634 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel organic catalysts for the direct enantioselective α-oxidation of carbonyl compounds
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Novel organic catalysts for the direct enantioselective α-oxidation of carbonyl compounds
چکیده انگلیسی

The proline-derived N-sulfonylcarboxamide-catalyzed direct enantioselective α-oxidation of ketones and aldehydes with nitrosobenzene is presented. The reactions proceed smoothly furnishing the corresponding α-aminoxylated compounds in good yields with up to >99% ee. The proline-derived N-sulfonylcarboxamides were also found to be excellent catalysts for the direct enantioselective nitroso Diels-Alder-type reaction between nitrosobenzene and α,β-unsaturated cyclic ketones yielding the corresponding bicyclic Diels-Alder adduct products with up to >99% ee. The proline-derived N-sulfonylcarboxamides represent a readily available and highly modular novel type of organic catalyst.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 46, Issue 19, 9 May 2005, Pages 3385-3389
نویسندگان
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