کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5280465 | 1385648 | 2005 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Uncatalysed Knoevenagel condensation in aqueous medium at room temperature Uncatalysed Knoevenagel condensation in aqueous medium at room temperature](/preview/png/5280465.png)
Knoevenagel condensation of various aromatic and heteroaromatic aldehydes with active methylene compounds like malononitrile, ethyl cyanoacetamide, ethyl cyanoacetate, barbituric acids, Meldrum's acid, dimedone and pyrazolone proceeds smoothly with stirring in an aqueous medium. The reactions occur at room temperature giving excellent yields of the products. The work-up procedure is very simple and the products do not require further purification.
Knoevenagel condensation of various aromatic and heteroaromatic aldehydes with active methylene compounds like malononitrile, ethyl cyanoacetamide, ethyl cyanoacetate, barbituric acids, Meldrum's acid, dimedone and pyrazolone proceeds smoothly with stirring in aqueous medium. The reactions occur at room temperature giving excellent yields of the products. The work-up procedure is very simple and the products do not require further purification.
Journal: Tetrahedron Letters - Volume 46, Issue 38, 19 September 2005, Pages 6453-6456