کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5281243 1385665 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Gold(I)-catalyzed one-pot reaction between 2-alkynylanilines and alkynols leading to the formation of C-3-substituted indoles: a case of formal carboamination of alkynes
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Gold(I)-catalyzed one-pot reaction between 2-alkynylanilines and alkynols leading to the formation of C-3-substituted indoles: a case of formal carboamination of alkynes
چکیده انگلیسی
A process involving gold(I)-catalyzed formal carboamination of alkynes for the synthesis of C-3-substituted indoles has been developed. The procedure utilizes easily accessible starting materials such as 2-alkynylanilines and alkynols. A series of C-3-functionalized indoles are accessible by using this one-pot strategy. Mechanistically, the reaction involves three catalytic cycles and each of them is essentially catalyzed by a single metal catalyst, that is, Ph3PAuOTf.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 51, Issue 11, 17 March 2010, Pages 1493-1496
نویسندگان
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