کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5281737 1385678 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microwave-assisted Friedländer synthesis of quinolines derivatives as potential antiparasitic agents
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Microwave-assisted Friedländer synthesis of quinolines derivatives as potential antiparasitic agents
چکیده انگلیسی

A series of substituted quinolines was developed via the Friedländer reaction employing microwave irradiation (MW), in the presence of a catalytic amount of hydrochloric acid. The products were obtained in good yields in 1.5-12 min and were tested in vitro against the parasites causative of malaria, leishmaniasis, sleeping sickness and Chagas' disease (TDR, WHO). Some of these compounds exhibited activity against Plasmodium falciparum and others resulted moderately active against Trypanosoma cruzi.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 47, Issue 50, 11 December 2006, Pages 8811-8815
نویسندگان
, , , , ,