کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5281934 | 1385681 | 2008 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Bitriazolyl acyclonucleosides with antiviral activity against tobacco mosaic virus Bitriazolyl acyclonucleosides with antiviral activity against tobacco mosaic virus](/preview/png/5281934.png)
Bitriazolyl acyclonucleosides were synthesized via the Huisgen reaction and then subjected to ammonolysis. The antiviral activity of these nucleosides against tobacco mosaic virus (TMV) was assessed. Like the previously described bitriazolyl compounds, these new bitriazolyl acyclonucleosides were found to show anti-TMV activity. This suggests that the bitriazolyl moieties are important structural features involved in the antiviral activity of these compounds.
Bitriazolyl acyclonucleosides were synthesized via the Huisgen reaction and then subjected to ammonolysis. The antiviral activity of these nucleosides against tobacco mosaic virus (TMV) was assessed. Like the previously described bitriazolyl compounds, these new bitriazolyl acyclonucleosides were found to show anti-TMV activity. This suggests that the bitriazolyl moieties are important structural features involved in the antiviral activity of these compounds.
Journal: Tetrahedron Letters - Volume 49, Issue 17, 21 April 2008, Pages 2804-2809