کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5282002 1385683 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of glycolipid analogs via highly regioselective macrolactonization catalyzed by lipase
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of glycolipid analogs via highly regioselective macrolactonization catalyzed by lipase
چکیده انگلیسی
Highly regioselective lipase catalyzed macrolactonization has been used in synthesizing first feedstock based glycolipid analogs. These macrolides containing common disaccharides maltose (4-O-α-d-glucopyranosyl-β-d-glucose) and melibiose (6-O-α-d-galactopyranosyl-β-d-glucose) were synthesized by employing chemoenzymatic methodologies. Maltose and Melibiose were coupled with methyl 15-hydroxy pentadecanoate and then subjected to a highly regioselective macrolactonization at the C-6″ position using Candida antarctica lipase-B to yield the desired products.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 47, Issue 49, 4 December 2006, Pages 8645-8649
نویسندگان
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